2-Chloropyrimidine-5-carboxylic acid

2-Chloropyrimidine-5-carboxylic acid - Names and Identifiers

Name	2-Chloropyrimidine-5-carboxylic acid
Synonyms	INT A 101789 CML-011 SA023574 2-CHLORO-5-CARBOXYPYRIMIDINE 5-Carboxy-2-chloropyrimidine 2-Chloropyrimidine-5-carboxylic acid 5-Pyrimidinecarboxylicacid, 2-chloro- 2-CHLORO-PYRIMIDINE-5-CARBOXYLIC ACID 5-Pyrimidinecarboxylic acid, 2-chloro- 5-Carboxy-2-chloropyrimidine, 5-Carboxy-2-chloro-1,3-diazine
CAS	374068-01-6
InChI	InChI=1/C5H3ClN2O2/c6-5-7-1-3(2-8-5)4(9)10/h1-2H,(H,9,10)

2-Chloropyrimidine-5-carboxylic acid - Physico-chemical Properties

Molecular Formula	C5H3ClN2O2
Molar Mass	158.54
Density	1.579±0.06 g/cm3(Predicted)
Melting Point	126-131 °C
Boling Point	411.4±18.0 °C(Predicted)
Flash Point	202.612°C
Vapor Presure	0mmHg at 25°C
Appearance	Powder or Crystalline Powder
Color	White to off-white
pKa	2.51±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.598

2-Chloropyrimidine-5-carboxylic acid - Risk and Safety

HS Code

29335990

2-Chloropyrimidine-5-carboxylic acid - Introduction

Acid is an organic compound with the chemical formula C5H3ClN2O2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
Acid is a white crystalline solid, insoluble in water at room temperature, soluble in organic solvents such as ethanol and dimethyl sulfoxide. It is weakly acidic and can react with bases to form the corresponding salts.

Use:
Acid is an important organic synthesis intermediate, which plays an important role in the preparation of drugs, pesticides and other organic compounds. It can be used in the synthesis of anti-tumor drugs, antiviral drugs, pesticides and other bioactive molecules.

Preparation Method:
Generally, the preparation of phosphonium acid is obtained by reacting 2-chloropyrimidine with sodium hydroxide, and then acidifying. The chemical reaction conditions and operational details of the specific steps may vary for different laboratories and experimental purposes.

Safety Information:
During operation, attention should be paid to avoid contact with skin, eyes and respiratory system to prevent inhalation of dust. During use and storage, it is necessary to maintain good ventilation and follow the safe handling of chemicals. If you accidentally come into contact with or breathe this compound, seek medical help immediately.

Last Update：2024-04-09 19:05:49